Daddy Longlegs are the most venomous spider in the world, but their fangs can't penetrate human skin

An urban legend states that they are the most venomous spider in the world, but that because their fangs are unable to penetrate human skin, they are harmless to humans. However, recent research has shown that pholcid venom has a relatively weak effect on insects. No similar research has been conducted to determine its effects on mammalian biology.^[1] In the MythBusters episode "Daddy Long-Legs" it was shown that the spider's fangs (0.25mm) could penetrate human skin (0.1mm) but that only a very mild burning feeling was felt for a few seconds^[2].

Sources:

1. Spider Myths - If it could only bite
2. "Buried in Concrete, Daddy—Longlegs, Jet Taxi", MythBusters, Episode 13, Discovery Channel, Original airing: February 15, 2004 [1]

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